Hypothesis Eczema Therapy Cream vs Perricone MD Neuropeptide Pro-Strength Moisturizer

Both Perricone MD Neuropeptide Pro-Strength Moisturizer and Hypothesis Eczema Therapy Cream offer rich hydration and support for skin barriers, but they cater to slightly different needs. The Perricone MD option includes a sophisticated blend of peptides and additional actives aimed at enhancing skin texture and appearance, while the Hypothesis cream focuses on soothing and protecting dry, sensitive skin with its colloidal oatmeal and ceramide-rich formula. The texture of the Hypothesis cream is also notably rich and cushioning, similar to the Perricone MD product, but it may be more suitable for those specifically dealing with eczema or extreme dryness. While both products share several beneficial ingredients, the presence of fragrance in the Perricone MD formula may be a concern for some users, whereas the Hypothesis cream is fragrance-free, making it a safer choice for sensitive skin types.

Match
80%
Price
$29.99
Category
Skincare
Type
Face Moisturizer
Ingredients
38 ingredients
Buy
Match
80%
Price
$189.00
Category
Skincare
Type
Face Moisturizer
Ingredients
56 ingredients
Buy

What's inside

What's inside

Key ingredients

Key ingredients

Benefits

Benefits

Concerns

Concerns

Ingredients Side-by-side

  1. COLLOIDAL OATMEALAbrasive, Absorbent, Bulking Agent, Skin Protectant
  2. WaterSolvent
  3. GlycerinDenaturant, Hair Conditioner, Humectant, Oral Care, Skin Protectant, Solvent, Viscosity Controller, Perfuming Agent, Fragrance, Humectant Skin Conditioner
  4. CAPRYLIC / CAPRIC TRIGLYCERIDEFragrance, Solvent, Perfuming Agent, Occlusive Skin Conditioner
  5. CETYL ALCOHOLEmollient Skin Conditioner, Emulsifying Surfactant, Emulsion Stabilizer, Foam-Boosting Surfactant, Fragrance, Opacifying Agent, Cleansing Surfactant, Viscosity Controller
  6. BIS-DIGLYCERYL POLYACYLADIPATE-2Emollient Skin Conditioner, Skin Conditioner
  7. JOJOBA ESTERSEmollient Skin Conditioner, Moisturizing, Skin Conditioner, Soothing Agent
  8. POLYGLYCERYL-2 STEARATEEmulsifying Surfactant
+30 more ingredients
  1. Butyrospermum Parkii ButterSkin Conditioner, Viscosity Controller, Emollient
  2. BisabololFragrance, Skin Conditioner, Soothing Agent
  3. Ceramide NPHair Conditioner, Other Skin Conditioner, Barrier Support
  4. CERAMIDE APHair Conditioner, Skin Conditioner
  5. CERAMIDE EOPHair Conditioner, Skin Conditioner
  6. PhytosphingosineHair Conditioner, Skin Conditioner, Barrier Support
  7. CholesterolEmollient Skin Conditioner, Emulsifying Surfactant, Skin Conditioner, Light Stabilizer, Viscosity Controller, Barrier Support, Emollient
  8. SODIUM PCAAntistatic, Hair Conditioner, Humectant, Skin Conditioner
  9. UREAAntistatic, Buffering Agent, Humectant, Skin Conditioner
  10. TREHALOSEHumectant, Moisturizing
  11. Sodium HyaluronateHumectant, Skin Conditioner
  12. HEXYLENE GLYCOLEmulsifying Surfactant, Skin Conditioner, Solvent, Cleansing Surfactant, Perfuming Agent
  13. POLYQUATERNIUM-51Film Former, Skin Conditioner
  14. TRIACETINAntimicrobial, Film Former, Fragrance, Plasticizer, Solvent
  15. Caprylyl GlycolDeodorant, Emollient Skin Conditioner, Hair Conditioner, Skin Conditioner, Preservative, Humectant
  16. SODIUM LAUROYL LACTYLATEEmulsifying Surfactant
  17. TocopherolAntioxidant, Fragrance, Other Skin Conditioner, Occlusive Skin Conditioner
  18. TOCOPHERYL ACETATEAntioxidant, Skin Conditioner
  19. DimethiconeAntifoaming, Emollient Skin Conditioner, Skin Conditioner, Skin Protectant, Emollient, Skin Protectant
  20. AMMONIUM ACRYLOYLDIMETHYLTAURATE / VP COPOLYMERViscosity Controller
  21. HYDROXYACETOPHENONEAntioxidant
  22. GLYCERYL STEARATEEmollient Skin Conditioner, Emulsifying Surfactant
  23. STEARYL ALCOHOLEmollient Skin Conditioner, Emulsifying Surfactant, Emulsion Stabilizer, Foam-Boosting Surfactant, Fragrance, Opacifying Agent, Refatting Agent, Cleansing Surfactant, Viscosity Controller
  24. CARBOMEREmulsion Stabilizer, Gel Former, Viscosity Controller
  25. Xanthan GumBinding Agent, Emulsifying Surfactant, Emulsion Stabilizer, Gel Former, Skin Conditioner, Cleansing Surfactant, Viscosity Controller, Thickener
  26. 1,2-HEXANEDIOLSkin Conditioner, Solvent
  27. Citric AcidBuffering Agent, Chelating Agent, Fragrance, Exfoliant, Active Ingredient, pH Adjuster
  28. Sodium HydroxideBuffering Agent, Denaturant, pH Adjuster
  29. TETRASODIUM GLUTAMATE DIACETATEChelating Agent
  30. EthylhexylglycerinDeodorant, Skin Conditioner, Preservative

Ingredients Side-by-side

  1. WaterSolvent
  2. GlycerinDenaturant, Hair Conditioner, Humectant, Oral Care, Skin Protectant, Solvent, Viscosity Controller, Perfuming Agent, Fragrance, Humectant Skin Conditioner
  3. CAPRYLIC / CAPRIC TRIGLYCERIDEFragrance, Solvent, Perfuming Agent, Occlusive Skin Conditioner
  4. CETEARYL ALCOHOLEmollient Skin Conditioner, Emulsifying Surfactant, Emulsion Stabilizer, Foam-Boosting Surfactant, Opacifying Agent, Cleansing Surfactant, Viscosity Controller
  5. DimethiconeAntifoaming, Emollient Skin Conditioner, Skin Conditioner, Skin Protectant, Emollient, Skin Protectant
  6. Butyrospermum Parkii ButterSkin Conditioner, Viscosity Controller, Emollient
  7. CETEARYL OLIVATEEmollient Skin Conditioner, Emulsifying Surfactant, Emulsion Stabilizer, Hair Conditioner, Slip Modifier
  8. SORBITAN OLIVATEEmulsifying Surfactant
+48 more ingredients
  1. SODIUM PCAAntistatic, Hair Conditioner, Humectant, Skin Conditioner
  2. HYDROXYETHYL ACRYLATE / SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMEREmulsion Stabilizer, Viscosity Controller
  3. Butylene GlycolHumectant, Fragrance, Skin Conditioner, Solvent, Viscosity Controller
  4. HYDROXYACETOPHENONEAntioxidant
  5. TocopherolAntioxidant, Fragrance, Other Skin Conditioner, Occlusive Skin Conditioner
  6. C15-23 ALKANESolvent
  7. SODIUM COCOYL GLUTAMATECleansing Agent, Cleansing Surfactant
  8. 1,2-HEXANEDIOLSkin Conditioner, Solvent
  9. Caprylyl GlycolDeodorant, Emollient Skin Conditioner, Hair Conditioner, Skin Conditioner, Preservative, Humectant
  10. AllantoinSkin Conditioner, Skin Protectant, Soothing Agent, Skin Protectant
  11. SODIUM LAUROYL LACTYLATEEmulsifying Surfactant
  12. Decyl GlucosideCleansing Agent, Emulsion Stabilizer, Cleansing Surfactant, Surfactant
  13. FragranceFragrance
  14. BisabololFragrance, Skin Conditioner, Soothing Agent
  15. TETRASODIUM GLUTAMATE DIACETATEChelating Agent
  16. CARBOMEREmulsion Stabilizer, Gel Former, Viscosity Controller
  17. SODIUM LACTATEBuffering Agent, Humectant, Keratolytic
  18. HELIANTHUS ANNUUS SEED OILEmollient Skin Conditioner, Solvent, Other Skin Conditioner, Occlusive Skin Conditioner
  19. Citric AcidBuffering Agent, Chelating Agent, Fragrance, Exfoliant, Active Ingredient, pH Adjuster
  20. PhenoxyethanolAntimicrobial, Preservative
  21. Ceramide NPHair Conditioner, Other Skin Conditioner, Barrier Support
  22. POLYSORBATE 20Emulsifying Surfactant, Cleansing Surfactant
  23. GLYCERYL STEARATEEmollient Skin Conditioner, Emulsifying Surfactant
  24. Sodium HyaluronateHumectant, Skin Conditioner
  25. MALUS DOMESTICA FRUIT CELL CULTURE EXTRACTSkin Conditioner
  26. CETEARETH-25Cleansing Agent, Emulsifying Surfactant, Cleansing Surfactant
  27. CERAMIDE APHair Conditioner, Skin Conditioner
  28. CholesterolEmollient Skin Conditioner, Emulsifying Surfactant, Skin Conditioner, Light Stabilizer, Viscosity Controller, Barrier Support, Emollient
  29. PhytosphingosineHair Conditioner, Skin Conditioner, Barrier Support
  30. Xanthan GumBinding Agent, Emulsifying Surfactant, Emulsion Stabilizer, Gel Former, Skin Conditioner, Cleansing Surfactant, Viscosity Controller, Thickener
  31. EthylhexylglycerinDeodorant, Skin Conditioner, Preservative
  32. UBIQUINONEAntioxidant, Skin Conditioner
  33. CETEARETH-6Emulsifying Surfactant, Cleansing Surfactant
  34. PALMITOYL PENTAPEPTIDE-4Skin Conditioner
  35. PTEROCARPUS MARSUPIUM BARK EXTRACTHair Conditioner, Antioxidant, Emollient Skin Conditioner
  36. STEARYL ALCOHOLEmollient Skin Conditioner, Emulsifying Surfactant, Emulsion Stabilizer, Foam-Boosting Surfactant, Fragrance, Opacifying Agent, Refatting Agent, Cleansing Surfactant, Viscosity Controller
  37. Palmitoyl Tripeptide-1Skin Conditioner, Active Ingredient
  38. PALMITOYL TETRAPEPTIDE-7Other Skin Conditioner
  39. LECITHINAntistatic, Emollient Skin Conditioner, Emulsifying Surfactant, Skin Conditioner
  40. Potassium SorbateFragrance, Preservative
  41. ACETIC ACIDBuffering Agent, Fragrance
  42. ACETYL HEXAPEPTIDE-8Humectant, Skin Conditioner
  43. CERAMIDE EOPHair Conditioner, Skin Conditioner
  44. NICOTIANA BENTHAMIANA OCTAPEPTIDE-30 SH-OLIGOPEPTIDE-2Hair Conditioner, Other Skin Conditioner
  45. CITRONELLOLPerfuming Agent
  46. HYDROXYCITRONELLALPerfuming Agent
  47. LimoneneDeodorant, Solvent, Perfuming Agent, Fragrance Allergen
  48. LINALOOLDeodorant, Perfuming Agent

Ingredients Explained

Water

Solvent · Shared

Aqua, commonly known as water, serves primarily as a solvent in cosmetic formulations. It is the most abundant ingredient in many products and is essential for dissolving other ingredients, facilitating their application and absorption on the skin. Formulators often add Aqua to create a suitable texture and consistency, ensuring that products are easy to spread and apply. Additionally, water can help to hydrate the skin, making it a vital component in many moisturizing formulations.

Glycerin

Denaturant, Hair Conditioner, Humectant, Oral Care, Skin Protectant, Solvent, Viscosity Controller, Perfuming Agent, Fragrance, Humectant Skin Conditioner · Shared

Glycerin, also known as Glycerine, is a naturally occurring compound that serves primarily as a humectant in cosmetic formulations. This means it has the ability to attract moisture from the environment and bind it to the skin, helping to maintain hydration levels. Due to its effective moisturizing properties, formulators often include Glycerin in products to enhance skin softness and elasticity, making it a popular choice in various skincare and cosmetic formulations.

CAPRYLIC / CAPRIC TRIGLYCERIDE

Fragrance, Solvent, Perfuming Agent, Occlusive Skin Conditioner · Shared

CAPRYLIC/CAPRIC TRIGLYCERIDE is a mixed triester derived from caprylic and capric acids, which are medium-chain fatty acids. This ingredient is commonly used in cosmetics for its functions as a skin-conditioning agent, providing an occlusive barrier that helps to retain moisture in the skin. Additionally, it serves as a solvent and fragrance component, enhancing the overall sensory experience of cosmetic formulations. Formulators may add CAPRYLIC/CAPRIC TRIGLYCERIDE to improve texture and spreadability, making products feel smoother and more luxurious on the skin.

Butyrospermum Parkii Butter

Skin Conditioner, Viscosity Controller, Emollient · Shared

Butyrospermum Parkii Butter, commonly known as Shea Butter, is a natural fat extracted from the nuts of the shea tree. It is primarily used in cosmetics as an emollient, which means it helps to soften and smooth the skin by creating a barrier that locks in moisture. This characteristic makes it a popular choice for formulations aimed at hydrating and nourishing the skin. Formulators may add Butyrospermum Parkii Butter to enhance the texture of products, providing a rich, creamy feel while also contributing to the overall moisturizing properties of the formulation.

Bisabolol

Fragrance, Skin Conditioner, Soothing Agent · Shared

Bisabolol is a naturally occurring compound often derived from chamomile. It is primarily known for its skin-conditioning properties, making it a popular ingredient in various cosmetic formulations. Formulators may add Bisabolol to enhance the moisturizing effects of products, as it helps to soothe and soften the skin. Additionally, its anti-inflammatory characteristics can contribute to a more comfortable application experience, particularly in formulations aimed at sensitive or irritated skin.

Ceramide NP

Hair Conditioner, Other Skin Conditioner, Barrier Support · Shared

Ceramide NP is a type of lipid molecule that plays a crucial role in maintaining the skin's natural barrier. It is a key component of the stratum corneum, the outermost layer of the skin, helping to retain moisture and protect against environmental stressors. In cosmetic formulations, Ceramide NP is often included for its ability to support skin hydration and improve the overall texture and resilience of the skin. Formulators may add it to products to enhance skin barrier function, making it beneficial for dry or compromised skin types.

CERAMIDE AP

Hair Conditioner, Skin Conditioner · Shared

CERAMIDE AP is a type of ceramide, which is a lipid molecule naturally found in the skin and hair. It plays a crucial role in maintaining the skin's barrier function and hydration levels. In cosmetic formulations, CERAMIDE AP is primarily used for its skin-conditioning and hair-conditioning properties, helping to improve moisture retention and enhance the overall texture and appearance of both skin and hair. Formulators may add it to products to support the skin's natural barrier, promote softness, and provide a protective effect against environmental stressors.

CERAMIDE EOP

Hair Conditioner, Skin Conditioner · Shared

CERAMIDE EOP is a type of ceramide, a lipid molecule that plays a crucial role in maintaining the skin's barrier function and overall hydration. In cosmetics, it is primarily used for its skin-conditioning and hair-conditioning properties. Formulators often add CERAMIDE EOP to products to help restore and reinforce the skin's natural barrier, which can be beneficial for improving moisture retention and enhancing the texture of both skin and hair. Its ability to mimic natural lipids makes it a valuable ingredient for promoting a healthy appearance and feel.